Total antibiotic use per 1000 persons per day
Total Defined Daily Dose (DDD) purchases of systemic antibiotic drugs prescriptions (numerator), among The total population (denominator)
Antibiotics are among the most commonly used drugs; however, their effectiveness is consistently decreasing due to the increasing global spread of antimicrobial resistance. The evolvement of the antimicrobial resistance crisis depends on the scope and way antibiotics are used, making careful follow-up of their use a public health priority. Unnecessary use of broad-spectrum antimicrobials is a major contributor to the emergence and spread of antimicrobial resistance .
Total Defined Daily Dose (DDD) purchases of systemic antibiotic drugs prescriptions in the measurement year
The total population
 Michael, Carolyn & Dominey-Howes, Dale & Labbate, Maurizio. (2014). The Antimicrobial Resistance Crisis: Causes, Consequences, and Management. Frontiers in public health. 2. 145. 10.3389/fpubh.2014.00145.